Wine: histamine content (0.12 mg/100 g)

Wine contains about 0.12 mg of histamine per 100 g, which is low for histamine.

0.12 mg/100 g

Reported range below detection to 3.42 mg per 100 g. Some samples had none detectable; the floor is a threshold, not a measurement.Concentrations vary with ripeness, storage and processing, so a single figure would be misleading.

By portion

PortionGramsHistamine
1 glass (5 oz)148 g0.18 mg

Source

“Wine: mean 3.63 mg/kg, maximum 34.25 mg/kg”
Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content? (Nutrients 2021;13(5):1395) · 2021 · CC BY 4.0
“Wine, white — mean 0.28 mg/kg (n=2); Sabaini (2009)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, white — mean 1.64 mg/kg (n=15); Agustini et al. (2014)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, white — mean 0.08, range 0.01–0.23 mg/kg (n=3); Camargo (2022)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Cabernet Franc — mean 0.49 mg/kg (n=6); Souza et al. (2005)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Cabernet Sauvignon — mean 0.92, range 0.23–1.73 mg/kg (n=8); Souza et al. (2005)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Cabernet Sauvignon — mean 3.8, range 3.79–3.8 mg/kg (n=6); Rossato (2005)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Merlot — mean 0.61, range 0.07–1.67 mg/kg (n=3); Souza et al. (2005)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Merlot — mean nd mg/kg (n=12); Manfroi et al. (2009)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Rose — mean nd mg/kg (n=3); Sabaini (2009)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Rose — mean 0.57, range 0.01–2.23 mg/kg (n=4); Camargo (2022)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Syrah — mean 1.69 mg/kg (n=3); Mota et al. (2009)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, Syrah — mean nd mg/kg (n=7); Nassur et al. (2017)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, red — mean 1.98 mg/kg (n=6); Sabaini (2009)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, red, dry — mean 3.5 mg/kg (n=19); Agustini et al. (2014)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, red, dry — mean 0.31, range 0.02–0.92 mg/kg (n=8); Camargo (2022)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, red, sweet — mean 2.4 mg/kg (n=13); Agustini et al. (2014)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, red, sweet — mean 0.13, range 0.07–0.19 mg/kg (n=2); Camargo (2022)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, table — mean 1.53 mg/kg (n=3); Daniel et al. (2015)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, table — mean 5.03, range nd–8.77 mg/kg (n=45); R. F. Braga (2015)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, table, white — mean 0.53 mg/kg (n=3); Lourenço et al. (2022)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, xisto — mean 2.52, range 0.6–4.5 mg/kg (n=63); Colimo (2013)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0
“Wine, sparkling — mean 0.4 mg/kg (n=5); Sabaini (2009)”
Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance (Food Science & Nutrition 2025;13:e71151) · 2025 · CC BY 4.0

Food composition data, not medical advice. Reported tolerance thresholds vary widely between individuals, so a value being high here does not mean you will react to it.